Current Members


Xiaoqiang Tang, Ph.D.

Postdoc—Research fellow

 

I first became interested in neuroscience when I was a college freshman. I read Eric Kandel’s book In Search of Memory: The Emergence of a New Science of Mind and was amazed by the intricate structure of the nervous system. Ever since then, I decided to pursue a research career in neuroscience. During my Ph.D. training in the laboratory of Dr. Wenyuan Wang at Shanghai Institute of Organic Chemistry (Chinese Academy of Sciences), I identified a conserved brain-specific lncRNA essential for maintaining the genome stability in the nervous system. Loss of this IncRNA causes DNA damage, neuronal loss, and motor deficits, defects that are widely observed in neurodegenerative diseases, such as ALS and FTD, suggesting that lncRNA plays vital roles in the nervous system. To better understand the mechanisms of these diseases, I went on to pursue my postdoctoral training in the laboratory of Dr. Ke Zhang. Currently, I am using Drosophila, immortalized cell lines, and patient iPS cells as models to understand how DNA damage contributes to C9ALS/FTD pathogenesis and identify therapeutic targets. It is my goal to become a research leader in the neurodegeneration field.

 

Education and Training

2019         Ph.D. Shanghai institute of Organic Chemistry, Chinese Academy of Sciences (PI: Wenyuan Wang)

2012 B.S. Biological Sciences, Anhui Normal University

Honors and Awards

2015-16 Merit student, University of Chinese Academy of Sciences

Publication

 

Contact Information: tang.xiaoqiang@mayo.edu